NAD+ and NADH play important roles in protecting us against a variety of seemingly unrelated illnesses. NAD+ and NADH are converted into each other via oxidation and reduction in many different metabolic activities throughout the body, and are thus known as a “redox couple.” 7 (While both NAD+ and NADH are important for health, this article will focus primarily on NAD+.) When it gains electrons (in a process known as reduction), it is turned into NADH. When the molecule goes through a reaction in which it loses electrons (known as oxidation), it forms NAD+. NAD can exist in two forms: NAD+ or NADH. It works best when given alongside other nutritional cofactors, like iron, vitamin B2 (riboflavin), ribose, CoQ10, and proline. (4) NAD+ can also be administered intravenously (IV) or taken as a nasal spray, sublingual lozenge, or oral capsule. (3) The body can salvage vitamin B 3 or nicotinamide mononucleotide from other reactions and recycle it back into NAD+ for use. “Vitamin B 3” is actually a collective term that refers to several NAD+ precursors, namely: niacin (or nicotinic acid), niacinamide (or nicotinamide), or nicotinamide riboside. (2) NAD+ can be made in the body from vitamin B 3. 4 (Side note: Some people think that it’s the tryptophan in turkey that makes people drowsy after Thanksgiving dinner, but the carbs and sugars consumed at dessert are more likely to be the culprit. Tryptophan can be found in foods like whole milk, tuna, chicken, and turkey. (1) The body can synthesize NAD+ out of the essential amino acid tryptophan. Our bodies get NAD+ from a few main sources: 2 Specifically, prolonged NAD+ deficiency compromises normal physiology, leading to a host of health problems like metabolic diseases, chronic fatigue, addiction, cancer, rapid aging, and neurodegenerative conditions. In general, higher NAD+ levels are associated with better health, 1 and problems with NAD+ production and function can lead to illness.
NAD+ levels vary depending on the time of day and other factors, and decline with age. NAD+ is found in all of our cells – but that doesn’t mean we have an endless supply of the coenzyme. NAD+ also helps repair damaged DNA and facilitates hundreds of other metabolic reactions in the body.
NAD+ is needed to help turn nutrients into energy, and is thus a key player in mitochondrial health. NAD+, or nicotinamide adenine dinucleotide, is a coenzyme – or enzyme “helper” that supports important reactions in the body. What the research says about nicotinamide adenine dinucleotide
0 kommentar(er)
